Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.800 strong 0.986 1038 879 1990 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.800 strong 0.993 850 1161 1990 2020
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.500 None 1.000 26 14 2010 2020
Entrez Id: 60500
Gene Symbol: BRCA3
BRCA3 		breast cancer 3 27 0.705 0.269 0.020 None 0.500 2 0 2017 2020
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.460 None 0.970 33 17 2007 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.460 None 1.000 32 6 2003 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.941 17 3 1994 2019
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 194 0.507 0.731 6.2E-17 0.410 None 1.000 14 9 2005 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.060 None 0.833 6 1 2000 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.040 None 1.000 4 0 2000 2019
Entrez Id: 353
Gene Symbol: APRT
APRT 		P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.010 None 1.000 1 0 2019 2019
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1 		P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2 		P13942 collagen type XI alpha 2 chain 399 0.435 0.846 0.70 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.420 None 1.000 19 7 2010 2018
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.160 None 0.875 8 7 2000 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1659
Gene Symbol: DHX8
DHX8 		Q14562 DEAH-box helicase 8 Enzyme 1 1.000 0.192 9.2E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.400 None 1.000 13 6 2004 2017
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29789
Gene Symbol: OLA1
OLA1 		Q9NTK5 Obg like ATPase 1 Enzyme modulator 18 0.780 0.269 5.8E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.050 None 1.000 5 0 2000 2016
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.400 None 1.000 3 1 2003 2016
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		Q92826 homeobox B13 90 0.573 0.462 3.7E-08 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B 		O15315 RAD51 paralog B 126 0.556 0.769 2.1E-15 0.100 None 1.000 1 1 2016 2016